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Multiscale modelling approach combining a kinetic model of glutathione metabolism with PBPK models of paracetamol and the potential glutathione depletion biomarkers ophthalmic acid and 5 oxoproline in humans and rats Integrative Biology (RSC Acetaminophen induces liver injury and depletes glutathione in mice brain: Prevention by Moringa oleifera extract ScienceDirect Silymarin prevents acetaminophen induced hepatotoxicity via up regulation of the glutathione conjugation capacity in mice ScienceDirect Good ol' paracetamol: 'But an overconsumption takes its toll' Journal of Anaesthesia Practice
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Multiscale modelling approach combining a kinetic model of glutathione  metabolism with PBPK models of paracetamol and the potential glutathione- depletion biomarkers ophthalmic acid and 5-oxoproline in humans and rats -  Integrative Biology (RSC
Acetaminophen induces liver injury and depletes glutathione in mice brain:  Prevention by Moringa oleifera extract - ScienceDirect
Silymarin prevents acetaminophen-induced hepatotoxicity via up-regulation  of the glutathione conjugation capacity in mice - ScienceDirect
Good ol' paracetamol: 'But an overconsumption takes its toll' - Journal of  Anaesthesia Practice

glutathione depletion paracetamol Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential

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